Skip to main content

Drug Interactions between histoplasmin and landiolol

This report displays the potential drug interactions for the following 2 drugs:

Edit list (add/remove drugs)

Interactions between your drugs

Moderate

histoplasmin landiolol

Applies to: histoplasmin and landiolol

Consumer information for this interaction is not currently available.

MONITOR: Beta-blockers may attenuate the response to epinephrine in the treatment of serious systemic reactions like anaphylaxis, which are possible following the administration of skin test antigens. During an anaphylactic reaction, the beneficial effects of epinephrine may be reduced due to impairment of compensatory cardiovascular responses and an increase in the release of mast cell mediators by the beta-blocker. Noncardioselective beta-blockers, in particular, can antagonize the bronchodilating effects of epinephrine by blocking beta-2 adrenergic receptors in the smooth muscles of the bronchial tree. Cardioselective beta-blockers may occasionally do the same, as beta-1 selectivity is not absolute and may be lost at higher dosages in susceptible patients. All beta-blockers can antagonize the cardiostimulatory effects of epinephrine by blocking beta-1 adrenergic receptors in the heart.

MANAGEMENT: Clinicians should be aware that patients receiving beta-blockers may be unresponsive to the usual doses of epinephrine used to treat serious allergic reactions like anaphylaxis, which could occur following the administration of skin test antigens. Some authorities suggest administration of glucagon in anaphylactic patients who are unresponsive to epinephrine. Relevant guidelines and product labeling should be consulted as indicated.

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


Report options

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.