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Drug Interactions between heparin and Ticlid

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

heparin ticlopidine

Applies to: heparin and Ticlid (ticlopidine)

MONITOR: Although therapy with heparin and ticlopidine often overlaps in clinical practice, the potential for additive anticoagulant effects and increased risk of bleeding should be considered.

MANAGEMENT: The manufacturer recommends that heparin be discontinued before initiating ticlopidine therapy. Patients who are to receive these drugs concomitantly should be closely monitored for signs of bleeding. Clinical trials have reported the concomitant use of heparin and ticlopidine in patients undergoing coronary stenting.

References (1)
  1. (2001) "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc

Drug and food interactions

Moderate

ticlopidine food

Applies to: Ticlid (ticlopidine)

ADJUST DOSING INTERVAL: The bioavailability and gastrointestinal tolerance of ticlopidine is enhanced by food.

MANAGEMENT: Patients may be advised to take ticlopidine with meals.

References (1)
  1. (2001) "Product Information. Ticlid (ticlopidine)." Syntex Laboratories Inc

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.