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Drug Interactions between heparin and landiolol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

heparin landiolol

Applies to: heparin and landiolol

Consumer information for this interaction is not currently available.

MONITOR: The concomitant administration of intravenous heparin with landiolol may reduce landiolol plasma levels and blood pressure. The coadministration of intravenous heparin with landiolol in patients undergoing cardiovascular surgery resulted in a 50% decrease in landiolol plasma concentrations, an increased landiolol circulation time, and heparin-induced hypotension. However, changes in heart rate values were not observed with concomitant use.

MANAGEMENT: Coadministration of intravenous heparin and landiolol be done with caution. If coadministration is clinically necessary, increased monitoring is advised. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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