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Drug Interactions between halothane and Rapiblyk

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

halothane landiolol

Applies to: halothane and Rapiblyk (landiolol)

MONITOR CLOSELY: The concomitant use of landiolol and inhaled anesthetics (e.g., isoflurane) may increase the risk of additive effects. Coadministration may potentiate the hypotensive effects of the inhaled anesthetic agent, potentially leading to additive effects on decreased heart rate, decreased blood pressure, and PR interval prolongation.

MANAGEMENT: Some authorities recommend careful titration of the landiolol infusion, dosage adjustment of either agent to achieve the desired effect, and close hemodynamic monitoring, if coadministration is clinically necessary (Canada). Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.

References (2)
  1. (2024) "Product Information. Sibboran (landiolol)." Trimedic Therapeutics Inc.
  2. (2024) "Product Information. Rapiblyk (landiolol)." AOP Orphan Pharmaceuticals GmbH

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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