Drug Interactions between gepirone and propoxyphene
This report displays the potential drug interactions for the following 2 drugs:
- gepirone
- propoxyphene
Interactions between your drugs
propoxyphene gepirone
Applies to: propoxyphene and gepirone
Using gepirone together with propoxyphene may increase the risk of experiencing a change in the electrical activity of your heart called QT prolongation, which can result in irregular heartbeats that can be life-threatening. You might be more susceptible to this risk if you have heart problems, uncontrolled hypothyroidism, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring of your electrocardiogram and blood tests to safely use both medications. You should seek immediate medical attention if you experience an irregular heartbeat or feeling dizzy, lightheaded, or faint during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
propoxyphene food
Applies to: propoxyphene
Do not use alcohol or medications that contain alcohol while you are receiving treatment with propoxyphene. This may increase nervous system side effects such as drowsiness, dizziness, lightheadedness, difficulty concentrating, and impairment in thinking and judgment. In severe cases, low blood pressure, respiratory distress, fainting, coma, or even death may occur. Do not use more than the recommended dose of propoxyphene, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
gepirone food
Applies to: gepirone
Food helps with the absorption of gepirone into the blood stream. You should take this medication with food at about the same time every day. You should not consume grapefruit or grapefruit products while taking this medication as they can increase the blood levels of gepirone in your body, putting you at a higher risk of serious side effects like serotonin syndrome or a change in the electrical activity of your heart called QT prolongation. Seek immediate medical attention if you experience any of the following signs or symptoms of these potentially life-threatening side effects: irregular or fast heartbeat, dizziness, lightheadedness, fainting, agitation, confusion, sweating, flushing, changes in blood pressure, seizures, hallucinations, or a loss of coordination. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.