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Drug Interactions between gefitinib and sodium bicarbonate

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

sodium bicarbonate gefitinib

Applies to: sodium bicarbonate and gefitinib

By reducing the acidity level in the stomach, medications like sodium bicarbonate may interfere with the absorption of gefitinib into the bloodstream and reduce its effectiveness. It is generally best to avoid using these medications together when possible. However, if you have no other alternatives for treatment, it is recommended that you take gefitinib 6 hours before or 6 hours after sodium bicarbonate to help minimize the impact of the interaction. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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