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Drug Interactions between gallium ga 68 dotatate and pasireotide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

pasireotide dotatate

Applies to: pasireotide and gallium ga 68 dotatate

ADJUST DOSING INTERVAL: Non-radioactive somatostatin analogs may interfere with the uptake of Ga-68 dotatate into neuroendocrine tumors by competitively binding to somatostatin receptors in tumor tissues. This may affect diagnostic imaging results.

MANAGEMENT: The manufacturer recommends imaging patients with gallium Ga-68 dotatate positron emission tomography (PET) just prior to dosing with long-acting somatostatin analogs. Short-acting formulations of somatostatin analogs can be used up to 24 hours before imaging with gallium Ga-68 dotatate.

References (1)
  1. (2016) "Product Information. Netspot (dotatate)." Advanced Accelerator Applications

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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