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Drug Interactions between flortaucipir F 18 and Urolene Blue

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Minor

methylene blue flortaucipir F-18

Applies to: Urolene Blue (methylene blue) and flortaucipir F 18

Flortaucipir F-18 has been reported to bind with low nanomolar affinity to monoamine oxidase-A (MAO-A) and monoamine oxidase-B (MAO-B) in vitro. In vivo, flortaucipir F-18 has differential uptake in neocortical areas containing aggregated tau protein. Flortaucipir F-18 positron emission tomography (PET) signal was slightly reduced in vivo by rasagiline, a MAO-B inhibitor, in low tau, high MAO-B areas of the brain such as the nucleus accumbens, putamen, and caudate. However, according to the flortaucipir F-18 manufacturer, there is little potential for MAO binding to affect flortaucipir F-18 scan interpretation in neocortical areas. It is not known if other MAO inhibitors (MAOIs) or agents with MAOI activity may interact.

References (1)
  1. (2022) "Product Information. Tauvid (flortaucipir F-18)." Lilly, Eli and Company

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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