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Drug interactions between Fleet Enema EXTRA and lactulose

Results for the following 2 drugs:
Fleet Enema EXTRA (sodium biphosphate/sodium phosphate)
lactulose

Interactions between your drugs

Moderate

sodium phosphate ↔ lactulose

Applies to:Fleet Enema EXTRA (sodium biphosphate/sodium phosphate) and lactulose

If you are using lactulose for the treatment of a condition known as portal-systemic encephalopathy, you should talk to your doctor before using it with sodium phosphate. The loose stools produced by treatment with sodium phosphate may make it difficult to know when you have achieved an adequate dosage of lactulose. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

sodium biphosphate ↔ lactulose

Applies to:Fleet Enema EXTRA (sodium biphosphate/sodium phosphate) and lactulose

If you are using lactulose for the treatment of a condition known as portal-systemic encephalopathy, you should talk to your doctor before using it with sodium biphosphate. The loose stools produced by treatment with sodium biphosphate may make it difficult to know when you have achieved an adequate dosage of lactulose. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

sodium biphosphate food

Applies to: Fleet Enema EXTRA (sodium biphosphate / sodium phosphate)

Oral medications may not be properly absorbed when they are taken within one hour before starting sodium biphosphate for bowel cleansing. Talk to your doctor or pharmacist to see if you should adjust the dosing schedule of your other medications before you begin bowel cleansing treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Stimulant and hyperosmotic laxatives

Therapeutic duplication

The recommended maximum number of medicines in the 'stimulant and hyperosmotic laxatives' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'stimulant and hyperosmotic laxatives' category:

  • sodium biphosphate (active ingredient in Fleet Enema EXTRA (sodium biphosphate/sodium phosphate))
  • lactulose

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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