Drug Interactions between Ferrlecit and vitamin e
This report displays the potential drug interactions for the following 2 drugs:
- Ferrlecit (sodium ferric gluconate complex)
- vitamin e
Interactions between your drugs
vitamin E sodium ferric gluconate complex
Applies to: vitamin e and Ferrlecit (sodium ferric gluconate complex)
MONITOR: Limited data suggest that vitamin E may diminish the therapeutic response to iron therapy in patients with iron deficiency anemia. The mechanism has not been established. In a group of 26 anemic children treated with iron dextran for 3 days, nine patients who also received vitamin E (200 units starting one day before iron dextran) had a reticulocyte response of only 4.4%, compared to 14.4% in the other patients. The patients who received vitamin E also had reduced hemoglobin levels and lower hematocrit.
MANAGEMENT: Patients receiving iron therapy for iron deficiency anemia should be monitored for potentially reduced hematologic response if vitamin E is administered concomitantly.
References
- Graeber JE, Williams ML, Oski FA (1977) "The use of intramuscular vitamin E in the premature infant. Optimum dose and iron interaction." J Pediatr, 90, p. 282-4
- Melhorn DK, Gross S (1969) "Relationships between iron-dextran and vitamin E in iron deficiency anemia in children." J Lab Clin Med, 74, p. 789-802
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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