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Drug interactions between fenofibrate and metformin / repaglinide

Results for the following 2 drugs:
fenofibrate
metformin/repaglinide

Interactions between your drugs

Moderate

repaglinide fenofibrate

Applies to: metformin / repaglinide and fenofibrate

Fenofibrate can increase the effects of repaglinide and cause your blood sugar levels to get too low. Symptoms of low blood sugar include headache, dizziness, drowsiness, nausea, hunger, tremor, weakness, sweating, and fast or pounding heartbeats. Talk with your doctor before using these medications together. You may need a dose adjustment or more frequent monitoring of your blood sugar if you have been using repaglinide and are starting treatment with fenofibrate. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

repaglinide food

Applies to: metformin / repaglinide

Grapefruit juice may increase the blood levels and effects of certain medications such as repaglinide. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with repaglinide. However, if you have been regularly consuming grapefruit or grapefruit juice with repaglinide, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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