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Drug Interactions between fecal microbiota, live and lefamulin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

lefamulin fecal microbiota, live

Applies to: lefamulin and fecal microbiota, live

If you are currently being treated with lefamulin, let your doctor know before you receive fecal microbiota, live. Using lefamulin together with fecal microbiota, live or 1 to 3 days before receiving treatment with fecal microbiota, live may decrease the effects of fecal microbiota, live. In addition, it may be advisable to avoid using any oral formulations of lefamulin for 8 weeks after treatment with fecal microbiota, live. Your doctor may want to separate the dosing times by a few days or weeks to reduce the risk of an interaction, or they may want to monitor you more closely to make sure the medications are working as intended. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

lefamulin food

Applies to: lefamulin

The following interaction applies only if you are taking lefamulin (Xenleta) orally:

Food may interfere with the absorption of lefamulin, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take lefamulin at least 1 hour before or 2 hours after a meal. It is best to avoid or limit the consumption of grapefruit and grapefruit juice during treatment with lefamulin, as it may increase blood levels of the medication and increase side effects. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.