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Drug interactions between Excedrin Migraine and guaifenesin / phenylephrine / pyrilamine

Results for the following 2 drugs:
Excedrin Migraine (acetaminophen/aspirin/caffeine)
guaifenesin/phenylephrine/pyrilamine

Interactions between your drugs

There were no interactions found in our database between Excedrin Migraine and guaifenesin / phenylephrine / pyrilamine. However, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Excedrin Migraine

A total of 679 drugs (3088 brand and generic names) are known to interact with Excedrin Migraine.

guaifenesin / phenylephrine / pyrilamine

A total of 904 drugs (5360 brand and generic names) are known to interact with guaifenesin / phenylephrine / pyrilamine.

Drug and food interactions

Moderate

pyrilamine food

Applies to: guaifenesin / phenylephrine / pyrilamine

Alcohol can increase the nervous system side effects of pyrilamine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with pyrilamine. Do not use more than the recommended dose of pyrilamine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

Switch to professional interaction data

Minor

caffeine food

Applies to: Excedrin Migraine (acetaminophen / aspirin / caffeine)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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