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Drug Interactions between estradiol and tirzepatide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

estradiol tirzepatide

Applies to: estradiol and tirzepatide

Tirzepatide may affect the blood levels and effects of oral contraceptives, which contain hormones such as estradiol. This may increase the risk of breakthrough bleeding and unintended pregnancy. Alternative, non-oral methods of birth control should be used, or add another method of birth control (such as condoms) to the oral contraceptive for 4 weeks after starting tirzepatide and for 4 weeks each time after the dose of tirzepatide is increased to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional if you have any questions or concerns, and for help in selecting an effective method of birth control that is best for you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

tirzepatide food

Applies to: tirzepatide

Tirzepatide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

estradiol food

Applies to: estradiol

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.