Drug Interactions between dronedarone and landiolol
This report displays the potential drug interactions for the following 2 drugs:
- dronedarone
- landiolol
Interactions between your drugs
dronedarone landiolol
Applies to: dronedarone and landiolol
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Concomitant use of landiolol with negative inotropes, medications that slow heart rate or cardiac conduction should be done with caution. Coadministration may result in additive suppression of cardiac function, atrioventricular (AV) conduction abnormalities, prolonged PR interval, and potentially additive heart-rate and blood pressure lowering effects. Landiolol alone is associated with increased risk of bradycardia and heart block, and therefore coadministration with these agents may potentiate these effects.
MANAGEMENT: If coadministration is clinically necessary, careful titration of the landiolol infusion and close hemodynamic monitoring is advised. Consultation with package labeling and relevant institutional protocols may be advisable for further guidance.
Drug and food interactions
dronedarone food
Applies to: dronedarone
Do not consume grapefruit or grapefruit juice during treatment with dronedarone unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of dronedarone to dangerous levels. This may increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. You may be more susceptible if you have a heart condition called congenital long QT syndrome, other cardiac diseases, conduction abnormalities, or electrolyte disturbances (for example, magnesium or potassium loss due to severe or prolonged diarrhea or vomiting). Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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