Can you take Dronabinol with Iophen DM NR?
1 drug interaction and 8 additional warnings found for the following 2 drugs:
- dronabinol
- Iophen DM NR (dextromethorphan/guaifenesin)
Drug interactions
Moderate drug interactions
Moderate:
dextromethorphan droNABinol
Applies to: Iophen DM NR (dextromethorphan / guaifenesin) and dronabinol
Using dextromethorphan together with droNABinol may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
Moderate food/lifestyle interactions
Moderate:
dextromethorphan Food/Lifestyle
Applies to: Iophen DM NR (dextromethorphan / guaifenesin)
Alcohol can increase the nervous system side effects of dextromethorphan such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with dextromethorphan. Do not use more than the recommended dose of dextromethorphan, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
Moderate:
droNABinol Food/Lifestyle
Applies to: dronabinol
Do not use alcohol while you are receiving treatment with droNABinol. This may increase nervous system side effects such as somnolence, dizziness, confusion, difficulty concentrating, and impairment in thinking and judgment. You should also avoid consuming grapefruit and grapefruit juice, as this may increase the blood levels and effects of droNABinol. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. Take droNABinol exactly as your doctor tells you to. Do not exceed the dose of droNABinol prescribed for you or use the medication more frequently or for a longer duration than prescribed by your doctor. Also, avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Disease interactions
6 potential interactions Applies to: 6 conditions, including Depression, Seizures, Psychosis, Drug Dependence, and Cardiovascular Conditions and Disorders.
Alcoholism
Moderate:
dronabinol
droNABinol has a moderate potential interaction with Alcoholism.
Some antiemetics as dronabinol and nabilone have a significant potential for abuse. Therapy with these drugs should be administered cautiously in patients with a history of substance abuse. It may be prudent to refrain from dispensing large quantities of dronabinol to these patients.
Cardiovascular Conditions and Disorders
Moderate:
dronabinol
droNABinol has a moderate potential interaction with Cardiovascular Conditions and Disorders.
The use of some antiemetics such as dronabinol and nabilone has been associated with occasional hypotension, possible hypertension, syncope or tachycardia. Therapy with these drugs should be administered cautiously in patients with cardiac disease.
Depression
Moderate:
dronabinol
droNABinol has a moderate potential interaction with Depression.
Some antiemetics such as dronabinol and nabilone may precipitate or exacerbate psychotic symptoms or anxiety, depression, hallucinations or psychosis. Therapy with these drugs should be administered cautiously in patients with a history of psychiatric disorders, emotional instability, or depression, and particularly if they are elderly. Careful psychiatric monitoring is advised.
Drug Dependence
Moderate:
dronabinol
droNABinol has a moderate potential interaction with Drug Dependence.
Some antiemetics as dronabinol and nabilone have a significant potential for abuse. Therapy with these drugs should be administered cautiously in patients with a history of substance abuse. It may be prudent to refrain from dispensing large quantities of dronabinol to these patients.
Psychosis
Moderate:
dronabinol
droNABinol has a moderate potential interaction with Psychosis.
Some antiemetics such as dronabinol and nabilone may precipitate or exacerbate psychotic symptoms or anxiety, depression, hallucinations or psychosis. Therapy with these drugs should be administered cautiously in patients with a history of psychiatric disorders, emotional instability, or depression, and particularly if they are elderly. Careful psychiatric monitoring is advised.
Seizures
Moderate:
dronabinol
droNABinol has a moderate potential interaction with Seizures.
Seizures and seizure- like activity have been reported in patients using dronabinol. Caution is advised in patients with history of a seizure disorder, as dronabinol may lower seizure threshold. Therapy should be discontinued immediately in patients who develop seizures and medical attention should be sought immediately.
Report options
More resources
dronabinol
A total of 411 drugs are known to interact with dronabinol.
- Dronabinol is in the drug class miscellaneous antiemetics.
- Dronabinol is used to treat the following conditions:
Iophen DM NR
A total of 375 drugs are known to interact with Iophen DM NR.
- Iophen dm nr is in the drug class upper respiratory combinations.
- Iophen dm nr is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.