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Can you take Doravirine with Focinvez?

1 drug interaction and 4 additional warnings found for the following 2 drugs:

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Drug interactions

Minor drug interactions

Minor:

fosaprepitant doravirine

Applies to: Focinvez (fosaprepitant) and doravirine

Information for this minor interaction is available on the professional version.

Food/lifestyle interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease interactions

4 potential interactions Applies to: 3 conditions, including Liver Disease, Renal Dysfunction, and Peritoneal dialysis.

Liver Disease

Moderate:

doravirine

Doravirine has a moderate potential interaction with Liver Disease.

Doravirine has not been studied in patients with severe liver dysfunction (Child-Pugh C); caution is recommended. No dosage adjustment of doravirine is needed in patients with mild or moderate liver dysfunction (Child-Pugh A or B).

Moderate:

Focinvez

The fosaprepitant in Focinvez has a moderate potential interaction with Liver Disease.

There are no clinical or pharmacokinetic data in patients with severe liver dysfunction (Child-Pugh score greater than 9); therefore, caution and additional monitoring for adverse reactions are recommended when using fosaprepitant in these patients.

Peritoneal dialysis

Moderate:

doravirine

Doravirine has a moderate potential interaction with Peritoneal dialysis.

Doravirine has not been adequately studied in patients with ESRD and has not been studied in patients receiving dialysis; caution is recommended. No dosage adjustment of doravirine is needed in patients with mild, moderate, or severe renal dysfunction.

Renal Dysfunction

Moderate:

doravirine

Doravirine has a moderate potential interaction with Renal Dysfunction.

Doravirine has not been adequately studied in patients with ESRD and has not been studied in patients receiving dialysis; caution is recommended. No dosage adjustment of doravirine is needed in patients with mild, moderate, or severe renal dysfunction.

More resources

doravirine

A total of 207 drugs are known to interact with doravirine.

Focinvez

A total of 471 drugs are known to interact with Focinvez.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.