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Drug Interactions between divalproex sodium and Pepto-Bismol

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

bismuth subsalicylate divalproex sodium

Applies to: Pepto-Bismol (bismuth subsalicylate) and divalproex sodium

Before taking bismuth subsalicylate, tell your doctor if you also use divalproex sodium. You may need dose adjustments or special tests in order to safely take both medications together. Small single doses of bismuth subsalicylate are unlikely to cause significant effects. However, if you take bismuth subsalicylate over a prolonged period of time you may need your divalproex sodium levels checked. You should notify your doctor if you have symptoms of fever, weakness, drowsiness, nausea, vomiting, or stomach pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

divalproex sodium food

Applies to: divalproex sodium

Alcohol can increase the nervous system side effects of divalproex sodium such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with divalproex sodium. Do not use more than the recommended dose of divalproex sodium, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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