Skip to main content

Drug Interactions between digitoxin and propylthiouracil

This report displays the potential drug interactions for the following 2 drugs:

Edit list (add/remove drugs)

Interactions between your drugs

Moderate

digitoxin propylthiouracil

Applies to: digitoxin and propylthiouracil

MONITOR: The clearance of digitalis glycosides may be reduced when a euthyroid state is achieved after the addition of antithyroid agents.

MANAGEMENT: Monitor the patient closely for altered efficacy and safety while achieving a euthyroid state or when antithyroid agents are added, discontinued, or dosing changes are made. Digitalis dose reductions may be required.

References (4)
  1. Doherty JE, Perkins WH (1966) "Digoxin metabolism in hypo- and hyperthyroidism. Studies with tritiated digoxin in thyroid disease." Ann Intern Med, 64, p. 489-507
  2. Frye RL, Braunwald E (1961) "Studies on digitalis. III: The influence of triiodothyronine on digitalis requirements." Circulation, 23, p. 376-82
  3. (2001) "Product Information. Propylthiouracil (propylthiouracil)." Lederle Laboratories
  4. (2001) "Product Information. Tapazole (methimazole)." King Pharmaceuticals Inc

Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer