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Drug Interactions between didanosine and nelfinavir

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

didanosine nelfinavir

Applies to: didanosine and nelfinavir

ADJUST DOSING INTERVAL: Nelfinavir should be administered with food, which may adversely affect the absorption of didanosine during concurrent administration due to increased acid in the stomach induced by food intake.

MANAGEMENT: Nelfinavir should be taken with food at least two hours before or one hour after didanosine.

References (1)
  1. (2001) "Product Information. Viracept (nelfinavir)." Agouron Pharma Inc

Drug and food interactions

Moderate

didanosine food

Applies to: didanosine

ADJUST DOSING INTERVAL: Didanosine bioavailability is decreased when administered with food. Loss of efficacy may result.

MANAGEMENT: Didanosine should be administered in the fasting state, at least 30 minutes before or more than 2 hours after eating.

References (1)
  1. (2002) "Product Information. Videx (didanosine)." Bristol-Myers Squibb

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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