Drug Interactions between demeclocycline and Prepopik

Demeclocycline and magnesium oxide should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of demeclocycline into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking magnesium oxide while your are being treated with demeclocycline. Otherwise, you should separate dosing by 2 to 4 hours, demeclocycline should be taken at least 2 hours before and not less than 6 hours after Suprep Bowel Prep (magnesium/potassium/sodium sulfates), or demeclocycline and magnesium oxide should be taken as directed by your healthcare provider. Talk to your healthcare provider if you are unsure whether your medications contain something that could potentially interact or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

The laxative effect of sodium picosulfate may be decreased when used during or following treatment with demeclocycline. Your doctor may prescribe a substitute for sodium picosulfate that is not affected by treatment with demeclocycline. You should let your doctor know if you experience signs and symptoms of low magnesium or potassium blood level such as weakness, tiredness, drowsiness, dizziness, confusion, tingling, numbness, muscle pain, cramps, nausea, or vomiting. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.