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Drug Interactions between DDAVP and prednisone

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

predniSONE desmopressin

Applies to: prednisone and DDAVP (desmopressin)

Using desmopressin together with predniSONE may increase the risk of hyponatremia, a condition associated with low levels of salt in the blood. In severe cases, hyponatremia can lead to seizures, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. You should seek medical attention if you experience loss of appetite, nausea, vomiting, headache, lethargy, irritability, difficulty concentrating, memory impairment, confusion, muscle spasm, weakness, unsteadiness, decreased urination, and/or sudden weight gain, as these may be symptoms of water intoxication and hyponatremia. Early diagnosis and treatment are essential to help prevent progression to more serious and life-threatening complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Minor

desmopressin food

Applies to: DDAVP (desmopressin)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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