Drug Interactions between dapsone and paraaminobenzoic acid

This report displays the potential drug interactions for the following 2 drugs:

Interactions between your drugs

Moderate

Applies to: dapsone and paraaminobenzoic acid

GENERALLY AVOID: Exogenous PABA may reverse the antimicrobial effect of dapsone.

MANAGEMENT: This drug combination should be avoided if possible.

References (2)

Degowin R, Eppes B, Carson P, Powell R (1966) "The effects of diaphenylsulfone (DDS) against chloroquine-resistant plasmodium falciparum." Bull World Health Organ, 34, p. 671-81
Bishop A (1965) "Resistance to diamino-diphenylsulphone in plasmodium gallinaceum." Parasitology, 55, p. 407-14

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major	Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate	Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor	Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown	No interaction information available.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

How to Prevent Deadly Drug Interactions

Some mixtures of medications can lead to serious and even fatal consequences.