Drug Interactions between Copper and trientine
This report displays the potential drug interactions for the following 2 drugs:
- Copper (copper gluconate)
- trientine
Interactions between your drugs
trientine copper gluconate
Applies to: trientine and Copper (copper gluconate)
Mineral supplements or mineral-containing medications such as copper gluconate can bind to trientine in the gastrointestinal tract, which may reduce the absorption of both trientine and the mineral. It is best to avoid taking these medications together when possible. However, if you must take both, you should try to separate the times of administration by at least two hours. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food/lifestyle interactions
trientine food/lifestyle
Applies to: trientine
Take trientine on an empty stomach 1 hour before or 2 hours after a meal and at least one hour apart from any other food, drug, or milk. You may experience reduced absorption of trientine in the presence of food or milk. The capsules should be swallowed whole with water and should not be opened or chewed.
trientine food/lifestyle
Applies to: trientine
Mineral supplements or mineral-containing medications such as multivitamin with minerals can bind to trientine in the gastrointestinal tract, which may reduce the absorption of both trientine and the mineral. It is best to avoid taking these medications together when possible. However, if you must take both, you should try to separate the times of administration by at least two hours. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Disease interactions
trientine Anemia Associated with Iron Deficiency
Applies to: Anemia Associated with Iron Deficiency
The use of trientine has been associated with exacerbating iron deficiency. Therapy with trientine should be administered cautiously in patients with iron deficiency. If iron supplements are administered, an interval of two hours between iron and trientine is recommended.
copper gluconate Biliary Obstruction
Applies to: Biliary Obstruction
The trace elements, copper and manganese, are excreted in the bile. Copper and manganese doses may need to be adjusted, reduced, or omitted in patients with liver disease or biliary obstruction.
copper gluconate Liver Disease
Applies to: Liver Disease
The trace elements, copper and manganese, are excreted in the bile. Copper and manganese doses may need to be adjusted, reduced, or omitted in patients with liver disease or biliary obstruction.
copper gluconate Malabsorption Syndrome
Applies to: Malabsorption Syndrome
The trace metals manganese, chromium, copper, selenium, and zinc are absorbed in the GI tract from dietary sources and following administration of oral supplements. GI absorption may be decreased in patients with malabsorption syndromes. Therefore, larger dosages may be required when these supplements are given orally. Parenteral administration may be appropriate.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.