Drug Interactions between cobimetinib and MetroGel
This report displays the potential drug interactions for the following 2 drugs:
- cobimetinib
- MetroGel (metronidazole topical)
Interactions between your drugs
No interactions were found between cobimetinib and MetroGel. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
cobimetinib
A total of 398 drugs are known to interact with cobimetinib.
- Cobimetinib is in the drug class multikinase inhibitors.
- Cobimetinib is used to treat the following conditions:
MetroGel
A total of 8 drugs are known to interact with MetroGel.
- Metrogel is in the drug class topical anti-rosacea agents.
- Metrogel is used to treat the following conditions:
Drug and food interactions
metroNIDAZOLE topical food
Applies to: MetroGel (metronidazole topical)
Consumption of alcoholic beverages or products containing alcohol or propylene glycol during treatment with metroNIDAZOLE topical may occasionally trigger a reaction in some patients similar to the disulfiram reaction, which includes unpleasant effects such as flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion. Rarely, more severe reactions may include abnormal heart rhythm, heart attack, heart failure, unconsciousness, convulsions, and even death. Patients treated with metroNIDAZOLE topical should avoid using any products containing alcohol or propylene glycol during and for up to 3 days until after completion of therapy. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
cobimetinib food
Applies to: cobimetinib
Grapefruit juice may increase the blood levels and effects of certain medications such as cobimetinib. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with cobimetinib. However, if you have been regularly consuming grapefruit or grapefruit juice with cobimetinib, do not alter the amounts of these products in your diet without first talking to your doctor or other healthcare professional. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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