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Drug interactions between clonazepam and Depakote ER

Results for the following 2 drugs:
clonazepam
Depakote ER (divalproex sodium)

Interactions between your drugs

Moderate

clonazepam ↔ divalproex sodium

Applies to:clonazepam and Depakote ER (divalproex sodium)

Before taking clonazePAM, tell your doctor if you also use divalproex sodium. You may need dose adjustments or special tests in order to safely take both medications together. This combination may affect seizure control and cause drowsiness. You should avoid driving until you know how these medications will affect you. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor first.

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Drug and food interactions

Moderate

divalproex sodium food

Applies to: Depakote ER (divalproex sodium)

Alcohol can increase the nervous system side effects of divalproex sodium such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with divalproex sodium. Do not use more than the recommended dose of divalproex sodium, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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