Drug Interactions between Clolar and pitolisant
This report displays the potential drug interactions for the following 2 drugs:
- Clolar (clofarabine)
- pitolisant
Interactions between your drugs
clofarabine pitolisant
Applies to: Clolar (clofarabine) and pitolisant
MONITOR: Coadministration with pitolisant may increase plasma concentrations of substrates of the hepatic and intestinal uptake transporter, organic cation transporter 1 (OCT1). Pitolisant has demonstrated inhibitory potential towards OCT1 in vitro. The clinical significance of this effect has not been established.
MANAGEMENT: Caution is recommended when pitolisant is administered with OCT1 substrates.
References (1)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Report options
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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