Skip to main content

Can you take Clascoterone topical with UAD Otic?

1 drug interaction and 6 additional warnings found for the following 2 drugs:

Add/remove drugs

Drug interactions

Minor drug interactions

Minor:

hydrocortisone otic clascoterone topical

Applies to: UAD Otic (hydrocortisone / neomycin / polymyxin b otic) and clascoterone topical

Information for this minor interaction is available on the professional version.

Food/lifestyle interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease interactions

6 potential interactions Applies to: 5 conditions, including Burns, External, Chronic Otitis Media, Ramsay Hunt Syndrome, Herpes Simplex Otitis Externa, and Perforated Tympanic Membrane.

Burns, External

Moderate:

UAD Otic

The neomycin topical in UAD Otic has a moderate potential interaction with Burns, External.

Topical aminoglycosides should not be used on serious burns. When applied locally, aminoglycosides are generally not absorbed to a significant extent through intact skin but readily absorbed through denuded, burned, or granulating skin. Systemic adverse effects of aminoglycosides include nephrotoxicity and ototoxicity to vestibular and auditory functions. In general, topical aminoglycosides should not be used on large areas of the body or for more than 7 days without medical supervision.

Chronic Otitis Media

Major:

UAD Otic

The hydrocortisone otic in UAD Otic has a major potential interaction with Chronic Otitis Media.

The use of medications that are intended for the treatment of otitis externa or other conditions of the external ear canal should generally be avoided, or otherwise approached with caution, in patients with a perforated tympanic membrane due to the risk of toxicity from medication that may get into the middle ear. Caution is also advised in patients with longstanding, chronic otitis media because of the possibility of a perforated tympanic membrane in such patients.

Herpes Simplex Otitis Externa

Major:

UAD Otic

The hydrocortisone otic in UAD Otic has a major potential interaction with Herpes Simplex Otitis Externa.

The use of otic preparations containing corticosteroids is contraindicated in patients with viral infections of the external canal including varicella and herpes simplex otitis externa. Corticosteroids may decrease host resistance to infectious agents, thus prolonging the course and/or exacerbating the severity of the infection while encouraging the development of new or secondary infection. Normally, corticosteroids may be administered with caution provided it is accompanied by appropriate anti-infective agents. However, otic preparations that are currently available lack effective antiviral agents.

Perforated Tympanic Membrane

Major:

UAD Otic

The neomycin topical in UAD Otic has a major potential interaction with Perforated Tympanic Membrane.

Like other aminoglycosides, neomycin is potentially ototoxic, both to vestibular and to auditory functions. Therapy with neomycin otic preparations should be administered cautiously in patients with chronic otitis media or a perforated tympanic membrane. The risk of ototoxicity may be increased if medication enters the middle ear.

Major:

UAD Otic

The hydrocortisone otic in UAD Otic has a major potential interaction with Perforated Tympanic Membrane.

The use of medications that are intended for the treatment of otitis externa or other conditions of the external ear canal should generally be avoided, or otherwise approached with caution, in patients with a perforated tympanic membrane due to the risk of toxicity from medication that may get into the middle ear. Caution is also advised in patients with longstanding, chronic otitis media because of the possibility of a perforated tympanic membrane in such patients.

Ramsay Hunt Syndrome

Major:

UAD Otic

The hydrocortisone otic in UAD Otic has a major potential interaction with Ramsay Hunt Syndrome.

The use of otic preparations containing corticosteroids is contraindicated in patients with viral infections of the external canal including varicella and herpes simplex otitis externa. Corticosteroids may decrease host resistance to infectious agents, thus prolonging the course and/or exacerbating the severity of the infection while encouraging the development of new or secondary infection. Normally, corticosteroids may be administered with caution provided it is accompanied by appropriate anti-infective agents. However, otic preparations that are currently available lack effective antiviral agents.

More resources

clascoterone topical

A total of 81 drugs are known to interact with clascoterone topical.

UAD Otic

A total of 30 drugs are known to interact with UAD Otic.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.