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Drug Interactions between cladribine and Cycrin

This report displays the potential drug interactions for the following 2 drugs:

  • cladribine
  • Cycrin (medroxyprogesterone)

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Interactions between your drugs


medroxyPROGESTERone cladribine

Applies to: Cycrin (medroxyprogesterone) and cladribine

Cladribine may reduce the blood levels and effectiveness of medroxyPROGESTERone, which may make it less reliable as a form of birth control. Alternative or additional methods of birth control such as condoms should be used during treatment with cladribine and for at least 4 weeks after the last dose in each treatment course to avoid unintended pregnancy. Talk to your gynecologist or other healthcare professional for help in selecting an effective method of birth control that is best for you. If you take hormone replacement for menopause, you should contact your doctor if you experience increased frequency or worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. In addition, male patients should take precautions to prevent pregnancy of their partner during treatment with cladribine and for at least 6 months after the last dose in each treatment course.

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Drug and food interactions


cladribine food

Applies to: cladribine

Cladribine oral products can bind to other medications. This may increase your risk of experiencing side effects. To avoid or minimize the interaction, cladribine should be taken at least 3 hours before or after other medications. Talk to your doctor if you have any questions or concerns, or if you have trouble separating the dosing times. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.