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Drug Interactions between Choledyl SA and Fluothane

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

halothane oxtriphylline

Applies to: Fluothane (halothane) and Choledyl SA (oxtriphylline)

GENERALLY AVOID: The administration of halothane following theophylline administration has been reported to result in ventricular tachycardia and, in one case, ventricular fibrillation. Halothane increases the arrhythmogenic potential of catecholamines. Theophylline appears to enhance the release of catecholamines.

MANAGEMENT: This combination should be avoided if possible. Halothane may interact in a similar manner with other methylxanthines.

References

  1. Roizen MF, Stevens WC "Multiform ventricular tachycardia due to the interaction of aminophylline and halothane." Anesth Analg 57 (1978): 738-41
  2. Richards W, Thompson J, Lewis G, et al. "Cardiac arrest associated with halothane anesthesia in a patient receiving theophylline." Ann Allergy 61 (1988): 83-4

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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