Can you take Chikungunya vaccine, live (cvx 317) with Daclizumab?

Daclizumab has a major potential interaction with Depression.

Depression-related events, including suicidal ideation or suicide attempt, have been reported with the use of daclizumab. If severe depression and/or suicidal ideation is present, consider discontinuation of therapy. Caution is recommended when using this agent in patients with previous depressive disorders.

Daclizumab has a moderate potential interaction with Eczema.

Serious skin reaction, including photosensitivity reactions, have occurred in patients treated with daclizumab. It is recommended to use daclizumab with caution in patients with a history of skin conditions, including eczema or psoriasis, as the use of this agent may exacerbate those conditions. If a patient develops a serious diffuse or inflammatory rash, it is recommended to evaluate the patient before the next dose and to discontinue treatment as appropriate.

Chikungunya vaccine, live (cvx 317) has a moderate potential interaction with Immunodeficiency.

The expected antibody responses may not be obtained when live attenuated vaccines and/or toxoids are administered to immunosuppressed persons, including those receiving immunosuppressive therapy. Caution and close monitoring is advised.

Daclizumab has a major potential interaction with Infection.

Infections of the upper respiratory tract, urinary tract, and viral infections, sometimes serious, have been reported with the use of daclizumab. It is recommended to avoid daclizumab in patients with a severe active infection. Monitor for signs and symptoms of an infection and consider withholding treatment until the infection resolves.

Daclizumab has a major potential interaction with Liver Disease.

Daclizumab use can cause life-threatening severe liver injury, including liver failure and autoimmune hepatitis. The use of daclizumab is contraindicated in patients with a history of autoimmune hepatitis or other autoimmune condition involving the liver, and in patients with preexisting liver disease of hepatic impairment, including ALT or AST at least two times the upper limit of normal. Prior to starting therapy with daclizumab, it is recommended to obtain serum transaminases (ALT and AST) and total bilirubin levels in all patients. Continue to monitor levels of transaminase levels and total bilirubin monthly, before each next dose, and follow transaminase levels and total bilirubin monthly for 6 months after the last dose of daclizumab. Treatment modifications are recommended based on serum transaminase and total bilirubin values. If patients develop clinical signs or symptoms suggestive of hepatic dysfunction, immediately discontinue treatment and promptly measure serum transaminases and total bilirubin. Discontinue treatment if autoimmune hepatitis is suspected.

Daclizumab has a moderate potential interaction with Psoriasis.

Serious skin reaction, including photosensitivity reactions, have occurred in patients treated with daclizumab. It is recommended to use daclizumab with caution in patients with a history of skin conditions, including eczema or psoriasis, as the use of this agent may exacerbate those conditions. If a patient develops a serious diffuse or inflammatory rash, it is recommended to evaluate the patient before the next dose and to discontinue treatment as appropriate.

Daclizumab has a major potential interaction with Tuberculosis, Active.

Tuberculosis has been reported with the use of daclizumab in countries where tuberculosis is endemic. Prior to initiating treatment, it is recommended to evaluate high-risk patients for tuberculosis infection. Patients testing positive for tuberculosis should be treated according to standard medical practice before initiating treatment with daclizumab.

Daclizumab has a major potential interaction with Tuberculosis, Latent.

Tuberculosis has been reported with the use of daclizumab in countries where tuberculosis is endemic. Prior to initiating treatment, it is recommended to evaluate high-risk patients for tuberculosis infection. Patients testing positive for tuberculosis should be treated according to standard medical practice before initiating treatment with daclizumab.