Can you take Chenodiol with Chlorotrianisene?
1 drug interaction and 5 additional warnings found for the following 2 drugs:
- chenodiol
- chlorotrianisene
Drug interactions
Moderate drug interactions
Moderate:
chlorotrianisene chenodeoxycholic acid
Applies to: chlorotrianisene and chenodiol
Talk to your doctor before using chenodeoxycholic acid together with chlorotrianisene. Prolonged use of chlorotrianisene can increase the risk for cholesterol gallstones and counteract the effectiveness of chenodeoxycholic acid in dissolving the stones. Your doctor may be able to suggest safer alternatives to chlorotrianisene while you are being treated with chenodeoxycholic acid. Otherwise, you may require more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
Minor food/lifestyle interactions
Minor:
chlorotrianisene Food/Lifestyle
Applies to: chlorotrianisene
Information for this minor interaction is available on the professional version.
Disease interactions
4 potential interactions Applies to: 4 conditions, including Primary Biliary Cholangitis, Gallstones, Liver Disease, and Cholangitis.
Cholangitis
Major:
chenodiol
The chenodeoxycholic acid in chenodiol has a major potential interaction with Cholangitis.
Chenodeoxycholic acid is contraindicated in the presence of known hepatocyte dysfunction or bile ductal abnormalities such as intrahepatic cholestasis, primary biliary cirrhosis or sclerosing cholangitis; a gallbladder confirmed as non-visualizing after two consecutive single doses of dye; radiopaque stones; or gallstone complications or compelling reasons for gallbladder surgery including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary gastrointestinal fistula.
Gallstones
Major:
chenodiol
The chenodeoxycholic acid in chenodiol has a major potential interaction with Gallstones.
Chenodeoxycholic acid is contraindicated in the presence of known hepatocyte dysfunction or bile ductal abnormalities such as intrahepatic cholestasis, primary biliary cirrhosis or sclerosing cholangitis; a gallbladder confirmed as non-visualizing after two consecutive single doses of dye; radiopaque stones; or gallstone complications or compelling reasons for gallbladder surgery including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary gastrointestinal fistula.
Liver Disease
Major:
chenodiol
The chenodeoxycholic acid in chenodiol has a major potential interaction with Liver Disease.
Chenodeoxycholic acid is contraindicated in the presence of known hepatocyte dysfunction or bile ductal abnormalities such as intrahepatic cholestasis, primary biliary cirrhosis or sclerosing cholangitis; a gallbladder confirmed as non-visualizing after two consecutive single doses of dye; radiopaque stones; or gallstone complications or compelling reasons for gallbladder surgery including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary gastrointestinal fistula.
Primary Biliary Cholangitis
Major:
chenodiol
The chenodeoxycholic acid in chenodiol has a major potential interaction with Primary Biliary Cholangitis.
Chenodeoxycholic acid is contraindicated in the presence of known hepatocyte dysfunction or bile ductal abnormalities such as intrahepatic cholestasis, primary biliary cirrhosis or sclerosing cholangitis; a gallbladder confirmed as non-visualizing after two consecutive single doses of dye; radiopaque stones; or gallstone complications or compelling reasons for gallbladder surgery including unremitting acute cholecystitis, cholangitis, biliary obstruction, gallstone pancreatitis, or biliary gastrointestinal fistula.
Report options
More resources
chenodiol
A total of 67 drugs are known to interact with chenodiol.
- Chenodiol is in the drug class gallstone solubilizing agents.
- Chenodiol is used to treat the following conditions:
chlorotrianisene
A total of 260 drugs are known to interact with chlorotrianisene.
- Chlorotrianisene is in the drug class estrogens.
- Chlorotrianisene is used to treat Postmenopausal Symptoms.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.