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Drug Interactions between cefpodoxime and esomeprazole

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

cefpodoxime esomeprazole

Applies to: cefpodoxime and esomeprazole

Using cefpodoxime together with esomeprazole is not recommended. By reducing stomach acid, esomeprazole can decrease the absorption and blood levels of cefpodoxime and make the medication less effective against infections. You may need to stop taking esomeprazole while you are being treated with cefpodoxime, or your doctor may want to prescribe a different antibiotic. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

cefpodoxime food

Applies to: cefpodoxime

Food can enhance the levels of cefpodoxime tablets in your body. Take the cefpodoxime tablets with food to increase absorption by the body. The cefpodoxime suspension can be taken with or without food. You should take cefpodoxime at the same time each day.

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Moderate

esomeprazole food

Applies to: esomeprazole

Food may interfere with the absorption of esomeprazole. Esomeprazole should be taken at least one hour before meals and at the same time every day. When esomeprazole is given to patients receiving continuous enteral nutrition (tube feedings), the tube feeding should be interrupted for at least 1 hour before and 1 hour after the dose of esomeprazole. This will make it easier for your body to absorb the medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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