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Drug Interactions between calcium gluceptate and digitoxin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

digitoxin calcium gluceptate

Applies to: digitoxin and calcium gluceptate

GENERALLY AVOID: The administration of parenteral calcium preparations, particularly by rapid IV injection, may precipitate serious cardiac arrhythmias in digitalized patients. The mechanism is probably related to the additive or synergistic inotropic effects of calcium and digitalis glycosides on the myocardium.

MANAGEMENT: Intravenous calcium should preferably not be used in patients receiving digitalis glycosides, or it should be given slowly or in small amounts to avoid high serum calcium concentrations. Patients should be monitored for development of arrhythmias.

References

  1. (2001) "Product Information. Lanoxin (digoxin)." Glaxo Wellcome
  2. (2001) "Product Information. Calcium Gluconate (calcium gluconate)." Fresenius Kabi USA, LLC
  3. (2001) "Product Information. PhosLo (calcium acetate)." Braintree

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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