Can you take Calcitriol topical with Calcium glycerophosphate?
1 drug interaction and 4 additional warnings found for the following 2 drugs:
- calcitriol topical
- calcium glycerophosphate
Drug interactions
Moderate drug interactions
Moderate:
calcium glycerophosphate calcitriol topical
Applies to: calcium glycerophosphate and calcitriol topical
The medication in calcitriol topical is absorbed through the skin into the bloodstream and may cause interactions with other medications. Using calcitriol topical together with calcium glycerophosphate may occasionally cause your blood calcium levels to become too high. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience signs and symptoms that may suggest excessive blood calcium levels such as dizziness, weakness, lethargy, muscle pain, headache, loss of appetite, nausea, vomiting, and seizures. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
4 potential interactions Applies to: 4 conditions, including Arrhythmia, Sarcoidosis, Renal Dysfunction, and Phosphate Imbalance.
Arrhythmia
Major:
calcium glycerophosphate
Calcium glycerophosphate has a major potential interaction with Arrhythmia.
Calcium is involved in cardiac muscle contraction and electrical impulse conduction. Therapy with calcium salt formulations (particularly IV) should be administered cautiously to patients with cardiac disease. Patients receiving cardiac glycosides and concomitant IV calcium may experience arrhythmias. Therapy with IV calcium should be administered slowly and at reduced dosages in patients with cardiac disease.
Phosphate Imbalance
Major:
calcium glycerophosphate
Calcium glycerophosphate has a major potential interaction with Phosphate Imbalance.
Elevated serum concentrations of calcium and phosphate can exceed the solubility level and result in calcium- phosphate precipitates that deposit in vascular and renal systems as well as other soft tissues of the body. Therapy with calcium should be administered with extreme caution in patients with hyperphosphatemia (hypoparathyroidism or severe renal impairment). Administration of oral calcium acetate or calcium carbonate, in addition to providing calcium, complexes phosphates within the GI tract. These complexes are eliminated in the feces. Clinical monitoring of serum calcium and phosphate concentrations is necessary.
Renal Dysfunction
Major:
calcium glycerophosphate
Calcium glycerophosphate has a major potential interaction with Renal Dysfunction.
Absorption of oral calcium formulations may be altered and elimination of calcium by the kidney decreased with renal impairment. Hyperphosphatemia occurs during renal failure. Calcium acetate or calcium carbonate, in addition to providing calcium, complexes phosphates within the GI tract. Calcium carbonate can partially correct metabolic acidosis associated with chronic renal failure. Clinical monitoring of renal function and serum calcium and phosphate concentrations is necessary.
Sarcoidosis
Major:
calcium glycerophosphate
Calcium glycerophosphate has a major potential interaction with Sarcoidosis.
Hypercalciuria, with or without hypercalcemia, may occasionally occur in patients with sarcoidosis. Elevated calcium levels may result from increased intestinal absorption of calcium, which is related to the extrarenal production of vitamin D by mononuclear phagocytes present within the sarcoid granuloma. Therapy with calcium salts should be administered cautiously and only if necessary in patients with sarcoidosis.
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More resources
calcitriol topical
A total of 66 drugs are known to interact with calcitriol topical.
- Calcitriol topical is in the drug class topical antipsoriatics.
- Calcitriol topical is used to treat Psoriasis.
calcium glycerophosphate
A total of 62 drugs are known to interact with calcium glycerophosphate.
- Calcium glycerophosphate is in the drug class minerals and electrolytes.
- Calcium glycerophosphate is used to treat Indigestion.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.