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Drug Interactions between bromfenac and revakinagene taroretcel

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

bromfenac revakinagene taroretcel ophthalmic

Applies to: bromfenac and revakinagene taroretcel

ADJUST DOSING INTERVAL: Coadministration of revakinagene taroretcel ophthalmic with drugs that can affect hemostasis such as anticoagulants, platelet inhibitors, thrombin inhibitors, thrombolytic agents, dextrans, and nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk of vitreous hemorrhage, which may result in temporary vision loss.

MANAGEMENT: The manufacturer of revakinagene taroretcel ophthalmic recommends temporarily interrupting antithrombotic medications before revakinagene taroretcel implantation. Patients should be advised to promptly report any signs of blurred vision, vision loss, floaters, or flashes of light. Clinicians should consult relevant literature, local and national treatment guidelines, and package labeling for further guidance.

References (1)
  1. (2025) "Product Information. Encelto (revakinagene taroretcel ophthalmic)." Neurotech Pharmaceuticals, Inc

Drug and food interactions

Moderate

bromfenac food

Applies to: bromfenac

ADJUST DOSE: In-vivo studies have demonstrated that the absorption of bromfenac is greatly reduced if the drug is taken within three and one-half hours following a high fat meal. The concomitant administration of a high fat meal has led to a 75% reduction in peak plasma concentrations and a 60% reduction in total area under the curve. The mechanism has not been described.

MANAGEMENT: An increased dosage of bromfenac (from 25 to 50 mg) may be needed if a high fat meal is consumed. The clinician may want to warn the patient about subtherapeutic analgesic effects if high fat meals are regularly consumed.

References (1)
  1. "Product Information. DurAct (bromfenac)." Wyeth-Ayerst Laboratories

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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