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Drug Interactions between Bonsity and digitoxin

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

digitoxin teriparatide

Applies to: digitoxin and Bonsity (teriparatide)

MONITOR: Concomitant use of digitalis preparations with human parathyroid hormone analogs may theoretically potentiate the risk of digitalis toxicity and arrhythmias. Human parathyroid hormone analogs such as teriparatide, palopegteriparatide, and abaloparatide can cause transient increases in serum calcium levels, and some reports have implicated hypercalcemia in cases of digitalis toxicity.

MANAGEMENT: Caution is recommended during concomitant use of digitalis and human parathyroid hormone analogs. Serum calcium and digitalis levels should be closely monitored, and the digitalis dosage adjusted as necessary. Patients should be advised to seek medical attention if they experience signs of digoxin toxicity such as nausea, anorexia, visual disturbances, slow pulse, or irregular heartbeat.

References

  1. (2002) "Product Information. Forteo (teriparatide)." Lilly, Eli and Company
  2. Benson CT, Voelker JR (2003) "Teriparatide has no effect on the calcium-mediated pharmacodynamics of digoxin." Clin Pharmacol Ther, 73, p. 87-94
  3. (2024) "Product Information. Yorvipath Prefilled Pen (palopegteriparatide)." Ascendis Pharma, Inc.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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