Drug Interactions between BioGaia ProTectis and Prepopik
This report displays the potential drug interactions for the following 2 drugs:
- BioGaia ProTectis (cholecalciferol/lactobacillus reuteri)
- Prepopik (citric acid/magnesium oxide/sodium picosulfate)
Interactions between your drugs
cholecalciferol magnesium oxide
Applies to: BioGaia ProTectis (cholecalciferol / lactobacillus reuteri) and Prepopik (citric acid / magnesium oxide / sodium picosulfate)
GENERALLY AVOID: Use of magnesium-containing products with a vitamin D analog may increase the risk of hypermagnesemia, particularly in chronic renal dialysis patients, due to potentially additive pharmacologic effects. Chronic hypermagnesemia may have a role in the pathogenesis of adynamic bone disease in dialysis patients.
MANAGEMENT: Patients on chronic renal dialysis treated with a vitamin D analog should avoid magnesium-containing products.
References
- "Product Information. Rocaltrol (calcitriol)." Roche Laboratories PROD (2001):
- "Product Information. Zemplar (paricalcitol)." Abbott Pharmaceutical PROD (2001):
- "Product Information. Hectorol (doxercalciferol)." Genzyme Corporation (2004):
- "Product Information. One-Alpha (alfacalcidol)." Pharmel Inc (2004):
Drug and food interactions
sodium picosulfate food
Applies to: Prepopik (citric acid/magnesium oxide/sodium picosulfate)
ADJUST DOSING INTERVAL: Bowel cleansing products can increase the gastrointestinal transit rate. Oral medications administered within one hour of the start of administration of the bowel cleansing solution may be flushed from the gastrointestinal tract and not properly absorbed.
MANAGEMENT: Patients should be advised that absorption of oral medications may be impaired during bowel cleansing treatment. Oral medications (e.g., anticonvulsants, oral contraceptives, antidiabetic agents, antibiotics) should not be administered during and within one hour of starting bowel cleansing treatment whenever possible. However, if concomitant use cannot be avoided, monitoring for reduced therapeutic effects may be advisable.
References
- "Product Information. Golytely (polyethylene glycol 3350 with electrolytes)." Braintree
- "Product Information. Prepopik (citric acid/Mg oxide/Na picosulfate)." Ferring Pharmaceuticals Inc (2022):
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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