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Drug Interactions between Bexxar and Iodotope

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

No interactions were found between Bexxar and Iodotope. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Bexxar

A total of 281 drugs are known to interact with Bexxar.

Iodotope

A total of 165 drugs are known to interact with Iodotope.

Drug and food interactions

Moderate

sodium iodide I-131 food

Applies to: Iodotope (sodium iodide-i-131)

MONITOR: Excessive intake of dietary iodine (e.g., iodised salt) may interfere with adequate uptake of radioiodide by the thyroid .

MANAGEMENT: A diet low in iodine is recommended before initiating therapy with sodium iodide I-131 or I-123.

References

  1. Cerner Multum, Inc. "Australian Product Information."

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Moderate

sodium iodide I-131 food

Applies to: Iodotope (sodium iodide-i-131)

ADJUST DOSING INTERVAL: Certain drugs may affect the pharmacokinetics, pharmacodynamics, and/or diagnostic results of radioiodides.

MANAGEMENT: Antithyroid agents such as carbimazole or propylthiouracil should generally be withheld for 1 week before administration of sodium iodide I-131 or I-123, and for a few days afterward. Salicylates, steroids, anticoagulants, antihistamines, antiparasitics, penicillins, sulfonamides, tolbutamide, thiopental, and nitroprusside should generally be withheld for 1 week. Amiodarone, lithium, and benzodiazepines should be withheld for at least 4 weeks.

References

  1. (2022) "Product Information. Sodium Iodide I-123 (sodium iodide I-123)." GE Healthcare

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Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Radiopharmaceutical agents

Therapeutic duplication

The recommended maximum number of medicines in the 'radiopharmaceutical agents' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'radiopharmaceutical agents' category:

  • Bexxar (iodine i 131 tositumomab)
  • Iodotope (sodium iodide-i-131)

Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer