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Drug Interactions between Betoptic and Corlopam

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

betaxolol ophthalmic fenoldopam

Applies to: Betoptic (betaxolol ophthalmic) and Corlopam (fenoldopam)

GENERALLY AVOID: The use of fenoldopam in combination with beta-blockers has not been studied. Theoretically, beta-blockers may potentiate the risk of severe, symptomatic hypotension by inhibiting the sympathetic reflex response to fenoldopam-induced blood pressure decreases.

MANAGEMENT: Concomitant use of fenoldopam with beta-blockers should be avoided if possible. The same precaution may be applicable to beta-blocker ophthalmic preparations, as they are systemically absorbed and can produce clinically significant systemic effects even at low or undetectable plasma levels. Moreover, since fenoldopam may cause a dose-dependent increase in intraocular pressure, caution should be exercised if it is administered to patients with glaucoma or ocular hypertension receiving ophthalmic beta-blockers.

References

  1. "Product Information. Corlopam (fenoldopam)." Neurex PROD (2001):

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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