Can you take Bethanechol with Tropicamide ophthalmic?
1 drug interaction and 13 additional warnings found for the following 2 drugs:
- bethanechol
- tropicamide ophthalmic
Drug interactions
Moderate drug interactions
Moderate:
tropicamide ophthalmic bethanechol
Applies to: tropicamide ophthalmic and bethanechol
Using bethanechol together with tropicamide ophthalmic may reduce the effectiveness of one or both medications.
Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications.
It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Food/lifestyle interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease interactions
13 potential interactions Applies to: 13 conditions, including High Blood Pressure, Asthma, Seizures, Hypotension, and Hyperthyroidism.
Asthma
Major:
bethanechol
Bethanechol has a major potential interaction with Asthma.
The use of cholinergic agonists is contraindicated in patients with uncontrolled reactive airway disease. Cholinergic agonists inhibits the hydrolysis of acetylcholine. The enhanced effect of acetylcholine produces constriction of the bronchi, increased bronchial secretions, and bronchospasm.
Gastrointestinal Obstruction
Major:
bethanechol
Bethanechol has a major potential interaction with Gastrointestinal Obstruction.
The use of cholinergic agonists is contraindicated in patients with peptic ulcers, mechanical GI obstruction, acute GI inflammatory conditions, or urinary obstruction. Cholinergic activity may result in an increase in gastric acid secretion, GI motility, and gastric contractions. In patients with urinary retention, urinary reflux may occur if the sphincter fails to relax when the bladder is contracted by cholinergic stimulation. The reflux of urine from the bladder can cause infection in the kidneys and upper urinary tract if bacteriuria is present.
Glaucoma/Intraocular Hypertension
Major:
tropicamide ophthalmic
Tropicamide ophthalmic has a major potential interaction with Glaucoma/Intraocular Hypertension.
Anticholinergic agents are contraindicated in patients with primary glaucoma, a tendency toward glaucoma (narrow anterior chamber angle), or adhesions (synechiae) between the iris and lens, as well as for the elderly and others in whom undiagnosed glaucoma or excessive pressure in the eye may be present. Because anticholinergics cause mydriasis, they may exacerbate these conditions.
Heart Block
Major:
bethanechol
Bethanechol has a major potential interaction with Heart Block.
The use of cholinergic agonists, such as bethanechol and pilocarpine, is contraindicated in patients with pronounced bradycardia, hypotension/hypertension, coronary artery disease or conduction disorders.
High Blood Pressure
Major:
bethanechol
Bethanechol has a major potential interaction with High Blood Pressure.
The use of cholinergic agonists, such as bethanechol and pilocarpine, is contraindicated in patients with pronounced bradycardia, hypotension/hypertension, coronary artery disease or conduction disorders.
Hyperthyroidism
Major:
bethanechol
Bethanechol has a major potential interaction with Hyperthyroidism.
The use of cholinergic agents may be contraindicated in patients with hyperthyroidism. Atrial fibrillation has occurred in hyperthyroid patients administered a cholinergic agonist.
Hypotension
Major:
bethanechol
Bethanechol has a major potential interaction with Hypotension.
The use of cholinergic agonists, such as bethanechol and pilocarpine, is contraindicated in patients with pronounced bradycardia, hypotension/hypertension, coronary artery disease or conduction disorders.
Ischemic Heart Disease
Major:
bethanechol
Bethanechol has a major potential interaction with Ischemic Heart Disease.
The use of cholinergic agonists, such as bethanechol and pilocarpine, is contraindicated in patients with pronounced bradycardia, hypotension/hypertension, coronary artery disease or conduction disorders.
Noninfectious Colitis
Major:
bethanechol
Bethanechol has a major potential interaction with Noninfectious Colitis.
The use of cholinergic agonists is contraindicated in patients with peptic ulcers, mechanical GI obstruction, acute GI inflammatory conditions, or urinary obstruction. Cholinergic activity may result in an increase in gastric acid secretion, GI motility, and gastric contractions. In patients with urinary retention, urinary reflux may occur if the sphincter fails to relax when the bladder is contracted by cholinergic stimulation. The reflux of urine from the bladder can cause infection in the kidneys and upper urinary tract if bacteriuria is present.
Parkinsonism
Major:
bethanechol
Bethanechol has a major potential interaction with Parkinsonism.
The use of cholinergic agonists may be contraindicated in patients with parkinsonism. Cholinergic agonists directly stimulates the parasympathetic nervous system inducing acetylcholinergic effects. Symptoms of Parkinson's disease may be exacerbated.
Peptic Ulcer
Major:
bethanechol
Bethanechol has a major potential interaction with Peptic Ulcer.
The use of cholinergic agonists is contraindicated in patients with peptic ulcers, mechanical GI obstruction, acute GI inflammatory conditions, or urinary obstruction. Cholinergic activity may result in an increase in gastric acid secretion, GI motility, and gastric contractions. In patients with urinary retention, urinary reflux may occur if the sphincter fails to relax when the bladder is contracted by cholinergic stimulation. The reflux of urine from the bladder can cause infection in the kidneys and upper urinary tract if bacteriuria is present.
Seizures
Major:
bethanechol
Bethanechol has a major potential interaction with Seizures.
The use of cholinergic agonists may be contraindicated in patients with seizure disorders. Cholinomimetics have been associated with convulsions.
Urinary Tract Obstruction
Major:
bethanechol
Bethanechol has a major potential interaction with Urinary Tract Obstruction.
The use of cholinergic agonists is contraindicated in patients with peptic ulcers, mechanical GI obstruction, acute GI inflammatory conditions, or urinary obstruction. Cholinergic activity may result in an increase in gastric acid secretion, GI motility, and gastric contractions. In patients with urinary retention, urinary reflux may occur if the sphincter fails to relax when the bladder is contracted by cholinergic stimulation. The reflux of urine from the bladder can cause infection in the kidneys and upper urinary tract if bacteriuria is present.
More resources
bethanechol
A total of 66 drugs are known to interact with bethanechol.
- Bethanechol is in the drug class miscellaneous genitourinary tract agents.
-
Bethanechol is used to treat the following conditions:
- Abdominal Distension
- GERD (off-label)
- Urinary Retention
tropicamide ophthalmic
A total of 29 drugs are known to interact with tropicamide ophthalmic.
- Tropicamide ophthalmic is in the drug class mydriatics.
- Tropicamide ophthalmic is used to treat the following conditions:
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.