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Drug Interactions between benznidazole and typhoid vaccine, live

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Major

typhoid vaccine, live benznidazole

Applies to: typhoid vaccine, live and benznidazole

If you are currently being treated with benznidazole or have been treated within the last 3 days, you should talk to your doctor before taking typhoid vaccine, live. Antibiotics like benznidazole can reduce the activity of the vaccine. To ensure adequate vaccine response, you should generally not take typhoid vaccine, live until at least 3 days after you complete your antibiotic therapy. If you have already started taking typhoid vaccine, live, it may be advisable to wait at least 3 days after the last dose of vaccine before using benznidazole, depending on the urgency of the antibiotic treatment. You should consult with your physician on what is the best course of action for you. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

benznidazole food

Applies to: benznidazole

Consumption of alcoholic beverages or products containing alcohol or propylene glycol during treatment with benznidazole is not recommended. Doing so may occasionally trigger a reaction in some patients similar to the disulfiram reaction, which includes unpleasant effects such as flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion. Rarely, more severe reactions may include abnormal heart rhythm, heart attack, heart failure, unconsciousness, convulsions, and even death. Patients treated with benznidazole should continue to avoid using any products containing alcohol or propylene glycol for at least 3 days until after completion of therapy. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer