Drug Interactions between avatrombopag and Jadenu
This report displays the potential drug interactions for the following 2 drugs:
- avatrombopag
- Jadenu (deferasirox)
Interactions between your drugs
No interactions were found between avatrombopag and Jadenu. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
avatrombopag
A total of 88 drugs are known to interact with avatrombopag.
- Avatrombopag is in the drug class platelet-stimulating agents.
- Avatrombopag is used to treat the following conditions:
Jadenu
A total of 598 drugs are known to interact with Jadenu.
- Jadenu is in the drug class chelating agents.
- Jadenu is used to treat the following conditions:
Drug and food interactions
deferasirox food
Applies to: Jadenu (deferasirox)
ADJUST DOSING INTERVAL: According to product labeling, the bioavailability of deferasirox was variably increased when taken with a meal.
MANAGEMENT: To ensure consistent plasma drug levels, deferasirox should be taken on an empty stomach 30 minutes before eating preferably at the same time everyday.
References (1)
- (2005) "Product Information. Exjade (deferasirox)." Novartis Pharmaceuticals
avatrombopag food
Applies to: avatrombopag
ADJUST DOSING INTERVAL: Food reduces the variability in oral absorption and bioavailability of avatrombopag. According to the product labeling, avatrombopag peak plasma concentration (Cmax) and systemic exposure (AUC) were not affected when administered with either a low-fat (500 calories; 3 g fat, 15 g proteins, 108 g carbohydrates) or high-fat (918 calories; 59 g fat, 39 g proteins, 59 g carbohydrates) meal. However, the variability of avatrombopag exposure was reduced by 40% to 60% with food, and the time to reach Cmax was delayed by 0 to 2 hours relative to the fasted state.
MANAGEMENT: To ensure consistent absorption and plasma drug levels, avatrombopag should be taken with food.
References (1)
- (2018) "Product Information. Doptelet (avatrombopag)." Dova Pharmaceuticals
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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