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Drug interactions between atenolol and Glucovance

Results for the following 2 drugs:
atenolol
Glucovance (glyburide/metformin)

Interactions between your drugs

Moderate

atenolol ↔ glyburide

Applies to:atenolol and Glucovance (glyburide/metformin)

Beta-blockers such as atenolol may increase the risk, severity, and/or duration of hypoglycemia (low blood sugar) in patients receiving glyBURIDE and certain other antidiabetic medications. In addition, beta-blockers may mask some of the symptoms of hypoglycemia such as tremor, palpitation and rapid heartbeat, making it more difficult to recognize an oncoming episode. Other symptoms of hypoglycemia such as headache, dizziness, drowsiness, nervousness, confusion, nausea, hunger, weakness, and perspiration are not affected. Talk to your doctor if you have any questions or concerns. You may need to monitor your blood glucose levels more frequently, especially if you are prone to developing hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

atenolol food

Applies to: atenolol

You may take atenolol with or without food, but take it the same way every time. Avoid consumption of large amounts of orange juice to prevent any changes in your atenolol levels. Orange juice could decrease the effectiveness of atenolol.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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