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Drug Interactions between Aspirin Buffered and Crestor

This report displays the potential drug interactions for the following 2 drugs:

  • Aspirin Buffered (aluminum hydroxide/aspirin/calcium carbonate/magnesium hydroxide)
  • Crestor (rosuvastatin)

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Interactions between your drugs

Moderate

aspirin calcium carbonate

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)

Using calcium carbonate together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aspirin aluminum hydroxide

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)

Using aluminum hydroxide together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aspirin magnesium hydroxide

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)

Using magnesium hydroxide together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

calcium carbonate rosuvastatin

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Crestor (rosuvastatin)

Taking the rosuvastatin and calcium carbonate doses too close together may interfere with the absorption of rosuvastatin and reduce its effectiveness. To prevent or minimize the interaction, rosuvastatin and calcium carbonate dosing should be separated by at least two hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aluminum hydroxide rosuvastatin

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Crestor (rosuvastatin)

Taking the rosuvastatin and aluminum hydroxide doses too close together may interfere with the absorption of rosuvastatin and reduce its effectiveness. To prevent or minimize the interaction, rosuvastatin and aluminum hydroxide dosing should be separated by at least two hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

magnesium hydroxide rosuvastatin

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Crestor (rosuvastatin)

Taking the rosuvastatin and magnesium hydroxide doses too close together may interfere with the absorption of rosuvastatin and reduce its effectiveness. To prevent or minimize the interaction, rosuvastatin and magnesium hydroxide dosing should be separated by at least two hours. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

aluminum hydroxide food

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)

Citrate, or citric acid, can increase the absorption of aluminum hydroxide. This may lead to elevated blood levels of aluminum, particularly in individuals with reduced kidney function, since aluminum is primarily eliminated by the kidneys. Excess aluminum may deposit and cause problems in various tissues including bone, brain, heart, liver, muscles, and spleen. Over time, weak bones, bone pain, fractures, skeletal deformity, brain disorders, and anemia may develop. Talk to your doctor before using aluminum hydroxide if you have kidney impairment or are on hemodialysis. You should avoid or limit the consumption of citrate-containing foods and beverages (e.G., soft drinks, citrus fruits, fruit juices) during treatment with aluminum hydroxide. Be aware that some effervescent and dispersible drug formulations may also contain citrate and should be restricted as well. Even if you do not have kidney problems, it may be best to separate the dosing of aluminum hydroxide and citrate-containing products by 2 to 3 hours. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

When aluminum hydroxide is taken during enteral nutrition therapy (tube feeding), the tube may get clogged. Therefore, aluminum hydroxide should not be mixed with or given after high-protein tube feedings. The dose should be separated from the feeding by as much as possible, and the tube should be thoroughly flushed before administration of the dose.

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Moderate

calcium carbonate food

Applies to: Aspirin Buffered (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)

Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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