Drug Interactions between Aspir 81 and avacopan

To ensure adequate absorption of the medication, avacopan should be taken with food. You should avoid or limit consumption of grapefruit, grapefruit juice, or any supplements that contain grapefruit extract during treatment with avacopan unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of avacopan. This may increase the risk and/or severity of side effects such as nausea, vomiting, diarrhea, infections, and liver problems. You should seek immediate medical attention if you develop signs and symptoms of liver damage such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and yellowing of the skin or eyes. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.