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Drug Interactions between Arduan and Demadex IV

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

pipecuronium torsemide

Applies to: Arduan (pipecuronium) and Demadex IV (torsemide)

MONITOR: Loop diuretics may enhance or decrease the effect of nondepolarizing neuromuscular blockers. The mechanism is unknown.

MANAGEMENT: The patient's respiratory status and level of neuromuscular blockade should be closely monitored. The dose of the neuromuscular blocker may require adjustment to achieve the desired effect.

References

  1. Scappaticci KA, Ham JA, Sohn YJ, Miller RD, Dretchen KL "Effects of furosemide on the neuromuscular junction." Anesthesiology 57 (1982): 381-8

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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