Drug Interactions between apomorphine and ondansetron
This report displays the potential drug interactions for the following 2 drugs:
- apomorphine
- ondansetron
Interactions between your drugs
ondansetron apomorphine
Applies to: ondansetron and apomorphine
CONTRAINDICATED: Severe hypotension and loss of consciousness has been reported during the concomitant use of apomorphine and ondansetron. The mechanism is unknown. Other 5-HT3 antagonists may also interact. In addition, dolasetron, palonosetron, and apomorphine have been associated with varying degrees of QT interval prolongation, which may increase the risk of torsades de pointes in susceptible patients.
MANAGEMENT: The concomitant use of apomorphine and 5-HT3 antagonists is contraindicated by the manufacturer.
References
- "Product Information. Anzemet (dolasetron)." Hoechst Marion Roussel PROD (2001):
- "Product Information. Aloxi (palonosetron)." MGI Pharma Inc (2003):
- "Product Information. Apokyn (apomorphine)." Mylan Pharmaceuticals Inc (2004):
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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