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Drug Interactions between anagrelide and Inocor I V

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

inamrinone anagrelide

Applies to: Inocor I V (inamrinone) and anagrelide

MONITOR: Anagrelide is an inhibitor of cyclic AMP phosphodiesterase (PDE) III and may potentiate the pharmacologic effects of drugs with similar properties such as inotropes milrinone, enoximone, inamrinone, olprinone, and cilostazol. Anagrelide alone has been associated with cardiovascular side effects such as vasodilation, palpitations, tachycardia, congestive heart failure, myocardial infarction, cardiomyopathy, cardiomegaly, complete heart block, and atrial fibrillation.

MANAGEMENT: Caution is advised if anagrelide is coadministered with other inotropes or PDE III inhibitors. The risk of potentially additive cardiovascular adverse effects should be considered.

References

  1. (2001) "Product Information. Agrylin (anagrelide)." Roberts Pharmaceutical Corporation

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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