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Drug Interactions between amphotericin b lipid complex and Nebupent

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

pentamidine amphotericin B lipid complex

Applies to: Nebupent (pentamidine) and amphotericin b lipid complex

MONITOR: The possible nephrotoxic side effects of pentamidine and amphotericin may be additive.

MANAGEMENT: Serum creatinine and BUN should be monitored closely during therapy with these two agents.

References

  1. Antoniskis D, Larsen RA "Acute, rapidly progressive renal failure with simultaneous use of amphotericin B and pentamidine." Antimicrob Agents Chemother 34 (1990): 470-2
  2. "Product Information. Abelcet (amphotericin B lipid complex)." Liposome Company Inc, The

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.